effect of p-cpa pretreatment on eeg power spectra in experimental open brain injury in rats

نویسندگان

rakesh kumar sinha

amit kumar ray

چکیده

continuous four hours eeg (electroencephalogram) recordings and its power spectrum analysis using fast fourier transform (fft) in urethane anesthetized male charles foster rats were performed in two groups: open brain injury and p-cpa (para-chlorophenylalanine) pretreated before brain injury, respectively, and compared with the eeg power spectrum of control rats. the eeg power spectrum analysis showed that there was a faster recovery in p-cpa pretreated group than the injury group of rats. the results showed that the p-cpa (a 5-ht inhibitor) prevents pathological changes following brain injury. simultaneously, the inference can also be drawn that eeg power spectrum analysis is a useful technique for monitoring the brain injury and its recovery following pharmacological treatments

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Effect of p-CPA Pretreatment on EEG Power Spectra in Experimental Open Brain Injury in Rats

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عنوان ژورنال:
iranian biomedical journal

جلد ۷، شماره ۳، صفحات ۱۱۹-۱۲۶

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